Clinical Trials

Protocol Name
Target Population
Status

High Dose Methylprednisolone and Rituximab
A Study of Combined High Dose Methylprednisolone and Rituximab as First-Line Treatment of Patients with Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia [UCSD-060256]

Open

Ofatumumab (Arzerra) in Combination with High-dose Methylprednisolone
A Phase II Study of Ofatumumab (Arzerra) in Combination with High-dose Methylprednisolone in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia [UCSD-100429]

Open
AMD3100 (Mozobil) and Rituximab
A Phase I/II Study of AMD3100 (Mozobil) and Rituximab in Patients with Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia [MOZ00207]

Open
ISF35 in Combination With Chemotherapy Fludarabine/Cyclophosphamide/Rituximab
A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL

Open
Revlimid + Rituximab CRC022
A Two-Arm, CLL Research Consortium (CRC022) Multi-Center Trial of Revlimid and Rituximab, for the Treatment of relapsed or refractory Patients with Chronic Lymphocytic Leukemia [UCSD-100205]
Open
Revlimid + Rituximab CRC014
Patients not wishing to undergo chemotherapy, the BCRF along with the CLL Research Consortium, have developed a front-line therapy using the well researched rituximab with Revlimid. (Phase II).

Closed To new accrual

ABT-263 (Navitoclax) in Combination with Either Fludarabine/Cyclophosphamide/Rituximab (FCR) or Bendamustine/Rituximab (BR)

A Phase I Study Evaluating the Safety of ABT-263 (Navitoclax) in Combination with Either Fludarabine/Cyclophosphamide/Rituximab (FCR) or Bendamustine/Rituximab (BR) in Subjects with Relapsed or Refractory Chronic Lymphocytic Leukemia [UCSD-090285]

Open

 

For More Information:
Please contact Shiela Hoff, R.N. (858) 822-5360 to see if you might be eligible for one of these studies.

For An Appointment:
To schedule an appointment in the UCSD CLL clinic with either Drs. Kipps, James, or Castro please contact  Carolina Bump at: (858) 534-5400

For a complete list of clinical trials for CLL at UCSD please consult the UCSD Cancer Center Website at:
Cancer.ucsd.edu
CRC000 - Tissue Core (non-therapeutic) This Study Sample Collection. The CRC tissue core study is one of the world's, if not the worlds, largest repositories of CLL materials. The collection of samples from patients around the world enable researchers to uncover CLL's mechanisms of action, with the hopeful result of developing curative stategies for patient with CLL. For more information contact Laura Rassenti at lrassenti@ucsd.edu or (858) 822-5989

Open